Distribuzione geografica
Continente #
NA - Nord America 15613
EU - Europa 5839
AS - Asia 2518
AF - Africa 21
Continente sconosciuto - Info sul continente non disponibili 17
SA - Sud America 12
OC - Oceania 9
Totale 24029
Nazione #
US - Stati Uniti d'America 15368
CN - Cina 2227
IT - Italia 1473
PL - Polonia 1453
IE - Irlanda 651
UA - Ucraina 528
SE - Svezia 443
DE - Germania 392
GB - Regno Unito 245
CA - Canada 244
FR - Francia 174
RU - Federazione Russa 145
TR - Turchia 131
BE - Belgio 79
AT - Austria 69
FI - Finlandia 62
IR - Iran 30
ES - Italia 29
IN - India 28
CH - Svizzera 21
NL - Olanda 21
VN - Vietnam 21
JP - Giappone 18
BJ - Benin 17
EU - Europa 17
PK - Pakistan 15
UZ - Uzbekistan 14
GR - Grecia 13
BG - Bulgaria 11
KR - Corea 9
AU - Australia 8
CL - Cile 8
DK - Danimarca 6
RO - Romania 5
SI - Slovenia 5
CZ - Repubblica Ceca 4
SG - Singapore 4
TH - Thailandia 4
AL - Albania 3
BR - Brasile 3
AM - Armenia 2
IL - Israele 2
MY - Malesia 2
NG - Nigeria 2
PT - Portogallo 2
SA - Arabia Saudita 2
TW - Taiwan 2
AE - Emirati Arabi Uniti 1
AF - Afghanistan, Repubblica islamica di 1
BA - Bosnia-Erzegovina 1
BN - Brunei Darussalam 1
EC - Ecuador 1
EE - Estonia 1
EG - Egitto 1
HK - Hong Kong 1
IQ - Iraq 1
KZ - Kazakistan 1
LB - Libano 1
LI - Liechtenstein 1
LV - Lettonia 1
MX - Messico 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
SC - Seychelles 1
Totale 24029
Città #
Woodbridge 3154
Fairfield 2163
Warsaw 1448
Chandler 1391
Ann Arbor 1154
Houston 1135
Seattle 878
Ashburn 863
Jacksonville 858
Cambridge 717
Wilmington 674
Dublin 584
Jinan 311
Mestre 261
Nanjing 248
Dearborn 228
Shenyang 218
Venezia 196
Andover 184
San Mateo 151
Mülheim 149
Boston 148
Hebei 139
Beijing 137
Izmir 129
Princeton 129
Venice 120
Ottawa 116
Toronto 115
San Diego 107
Boardman 96
Guangzhou 95
Hangzhou 93
Tianjin 92
Changsha 87
Nanchang 86
Zhengzhou 86
Taizhou 83
Altamura 81
Brussels 77
Haikou 77
Taiyuan 68
Ningbo 60
Vienna 55
Jiaxing 50
San Paolo di Civitate 50
Milan 49
Atlanta 48
Redwood City 42
London 37
Fuzhou 33
Des Moines 32
Menlo Park 31
Hefei 28
Saint Petersburg 28
Latiano 26
Bremen 21
Kunming 21
Dong Ket 20
Verona 20
Rome 18
Cotonou 17
Norwalk 17
Madrid 16
Moscow 15
Vicenza 15
Padova 13
Phoenix 13
Jesolo 11
Düsseldorf 10
Lanzhou 10
Palermo 9
Sofia 9
Udine 9
Zanjan 9
Portogruaro 8
Azzano Decimo 7
Chicago 7
Den Haag 7
Martellago 7
Reggio Nell'emilia 7
Detroit 6
Dolo 6
Eraclea 6
Henderson 6
Islamabad 6
Qingdao 6
Redmond 6
Southend 6
Tignale 6
Treviso 6
Winnipeg 6
Auburn Hills 5
Bogen 5
Clearwater 5
Ferrara 5
Frankfurt Am Main 5
Fremont 5
Hanover 5
Islington 5
Totale 20117
Nome #
Bottom-Up Synthesis of Carbon Nanoparticles with Higher Doxorubicin Efficacy 453
An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer 445
Extracellular Matrix and Colorectal Cancer: How Surrounding Microenvironment Affects Cancer Cell Behavior? 371
Synthesis of new allyl palladium complexes bearing purine-based NHC ligands with antiproliferative and proapoptotic activity on human ovarian cancer cell lines 370
Highly conserved non-coding sequences and the 18q critical region for short stature: A common mechanism of disease? 366
pRb controls estrogen receptor alpha protein stability and activity 364
Hyaluronan esters drive smad gene expression and signaling enhancing cardiogenesis in mouse embryonic and human mesenchymal stem cells 357
Biocompatible tailored zirconia mesoporous nanoparticles with high surface area for theranostic applications 354
Phamacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2 positive breast cancer 340
A functional biological network centered on XRCC3: a new possible marker of chemoradiotherapy resistance in rectal cancer patients 329
Palladacyclopentadienyl complexes bearing purine-based N-heterocyclic carbenes: A new class of promising antiproliferative agents against human ovarian cancer 326
Enhanced Chemotherapeutic Behavior of Open-Caged DNA@Doxorubicin Nanostructures for Cancer Cells 322
Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor 320
Virtual screening identifies a PIN1 inhibitor with possible antiovarian cancer effects 319
DNA nanotechnology for cancer therapy 313
A guide to PIN1 function and mutations across cancers 304
Decellularized colorectal cancer matrix as bioactive microenvironment for in vitro 3D cancer research 303
The Prolyl Isomerase Pin1 Acts Synergistically with CDK2 to Regulate the Basal Activity of Estrogen Receptor α in Breast Cancer 302
The history of nanoscience and nanotechnology: From chemical-physical applications to nanomedicine 299
Carbon-dots from sugars and ascorbic acid: Role of the precursors on morphology, properties, toxicity and drug uptake 295
4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors 292
Clinical Predictive Circulating Peptides in Rectal Cancer Patients Treated with Neoadjuvant Chemoradiotherapy 291
Synthesis and in-depth studies on the anticancer activity of novel palladacyclopentadienyl complexes stabilized by N-Heterocyclic carbene ligands 291
Liposomal delivery of a Pin1 inhibitor complexed with cyclodextrins as new therapy for high-grade serous ovarian cancer 279
An effective multi-stage liposomal DNA origami nanosystem for in vivo cancer therapy 278
The anticancer activity of an air-stable Pd(i)-NHC (NHC = N-heterocyclic carbene) dimer 268
Self-Therapeutic Nanomaterials for Cancer Therapy: A Review 267
Recent advances of electrochemical and optical enzyme-free glucose sensors operating at physiological conditions 258
Proof-of-Concept Multistage Biomimetic Liposomal DNA Origami Nanosystem for the Remote Loading of Doxorubicin 257
Highly Selective Salicylketoxime-Based Estrogen Receptor beta Agonists Display Antiproliferative Activities in a Glioma Model 245
MTHFR-1298 A > C (rs1801131) is a predictor of survival in two cohorts of stage II/III colorectal cancer patients treated with adjuvant fluoropyrimidine chemotherapy with or without oxaliplatin 243
Androgen receptor serine 81 mediates Pin1 interaction and activity 242
Alterations of the Plasma Peptidome Profiling in Colorectal Cancer Progression 242
Gene and MicroRNA Expression Are Predictive of Tumor Response in Rectal Adenocarcinoma Patients Treated With Preoperative Chemoradiotherapy 232
Exosomal doxorubicin reduces the cardiac toxicity of doxorubicin 229
A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017) 229
Adenosine receptor ligands in clinical trials 228
The ablation of EZH2 uncovers its crucial role in rhabdomyosarcoma formation 225
Identification and characterization of a new reversible MAGL inhibitor 224
Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors 224
Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: An investigation of the 1,8-naphthyridin-2(1H)-one scaffold 222
The Clinical translation of Organic Nanomaterials for Cancer Therapy: A Focus on Polymeric Nanoparticles, Micelles, Liposomes and Exosomes 219
Structural Optimization of 4-Chlorobenzoylpiperidine Derivatives for the Development of Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors 218
Epigenetic analysis of the critical region I for premature ovarian failure: Demonstration of a highly heterochromatic domain on the long arm of the mammalian X chromosome 216
CDK inhibitors: from the bench to clinical trials 215
RB gene family: Genome-wide ChIP approaches could open undiscovered roads 214
Strategies to optimize siRNA delivery to hepatocellular carcinoma cells 208
Pin1 and nuclear receptors: A new language? 207
Spatial and temporal expression of POF1B, a gene expressed in epithelia 206
Cyclic Ketoximes as Estrogen Receptor Selective Agonists 206
Osteopontin controls endothelial cell migration in vitro and in excised human valvular tissue from patients with calcific aortic stenosis and controls 206
Glucose Detection Devices and Methods Based on Metal–Organic Frameworks and Related Materials 206
Epigenetic control of the critical region for premature ovarian failure on autosomal genes translocated to the X chromosome: A hypothesis 205
New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents 205
Critical choices for modeling breast cancer in transgenic mouse models 204
Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1 203
Combined effects of PI3K and SRC kinase inhibitors with imatinib on intracellular calcium levels, autophagy, and apoptosis in CML-PBL cells 203
Dissecting Pin1 and phospho-pRb regulation 201
Palladium (0) olefin complexes bearing purine-based N-heterocyclic carbenes and 1,3,5-triaza-7-phosphaadamantane (PTA): Synthesis, characterization and antiproliferative activity toward human ovarian cancer cell lines 199
Fluorescent carbon nanoparticles in medicine for cancer therapy 197
A mutation in the Rett syndrome gene, MECP2, causes X-linked mental retardation and progressive spasticity in males 194
Identification of new fyn kinase inhibitors using a FLAP-based approach 193
A susceptibility gene for premature ovarian failure (POF) maps to proximal Xq28 193
Emerging molecular networks in Burkitt's lymphoma 192
Exosomes increase the therapeutic index of doxorubicin in breast and ovarian cancer mouse models 192
Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors 192
Pharmaco-metabolomics: An emerging "omics" tool for the personalization of anticancer treatments and identification of new valuable therapeutic targets 190
Improved Synthesis, Anticancer Activity and Electrochemical Characterization of Unusual Zwitterionic Palladium Compounds with a Ten‐Term Coordinative Ring 190
Chromosomal rearrangements in Xq and premature ovarian failure: Mapping of 25 new cases and review of the literature 189
Metabolomics biomarkers of frailty in elderly breast cancer patients 188
Fluorescent molecularly imprinted nanogels for the detection of anticancer drugs in human plasma 187
Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors 184
Nanomedicine in cancer pathology 183
R-Roscovitine (Seliciclib) prevents DNA damage-induced cyclin A1 upregulation and hinders non-homologous end-joining (NHEJ) DNA repair 177
X chromosome and ovarian failure 177
Supercritical CO2 extraction of natural antibacterials from low value weeds and agro-waste 175
Allyl palladium complexes bearing carbohydrate-based N-heterocyclic carbenes: Anticancer agents for selective and potent in vitro cytotoxicity 175
Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells 173
Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors 173
Fluorescent Carbon Nanoparticles in Medicine for Cancer Therapy: An Update 170
Ubiquitin-mediated protein degradation and methylation-induced gene silencing cooperate in the inactivation of the INK4/ARF locus in Burkitt's lymphoma cell lines 169
Polymer-mediated delivery of siRNAs to hepatocellular carcinoma: Variables affecting specificity and effectiveness 165
Targeting intracellular B2 receptors using novel cell-penetrating antagonists to arrest growth and induce apoptosis in human triple-negative breast cancer 164
Mutation analysis of two candidate genes for premature ovarian failure, DACH2 and POF1B 163
Pathological Role of Peptidyl-Prolyl Isomerase Pin1 in the Disruption of Synaptic Plasticity in Alzheimer's Disease 161
Inorganic Nanoparticles for Cancer Therapy: a Transition from Lab to Clinic 159
Research highlights. Protein kinase D3 is the genetic sensitizer of RAF inhibitor RAF265 in melanoma cells 155
Research highlights. Overcoming BRAF resistance to PLX4032 by AKT inhibition in PTEN-deficient melanoma cells 155
Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors 155
Rational development of MAGL inhibitors 154
Palladium(II)-η3-Allyl Complexes Bearing N-Trifluoromethyl N-Heterocyclic Carbenes: A New Generation of Anticancer Agents that Restrain the Growth of High-Grade Serous Ovarian Cancer Tumoroids 154
Characterization of the Saffron Derivative Crocetin as an Inhibitor of Human Lactate Dehydrogenase 5 in the Antiglycolytic Approach against Cancer 152
Synthesis and Antimicrobial Evaluation of Bis-morpholine Triazine Quaternary Ammonium Salts 147
Research highlights. MCL1 and FBW7 as new predictive candidate biomarkers of anti-tubulin agents 141
Cancer extracellular vesicles: Next-generation diagnostic and drug delivery nanotools 141
Upconversion-mediated Boltzmann thermometry in double-layered Bi2SiO5:Yb3+,Tm3+@SiO2hollow nanoparticles 137
Research highlights. PI3K/AKT/mTOR inhibitors would require PI3KCA-mutation analysis 136
Impact of DNA repair gene polymorphisms on the risk of biochemical recurrence after radiotherapy and overall survival in prostate cancer 134
Sustainable triazine-derived quaternary ammonium salts as antimicrobial agents 131
Application of MM-PBSA methods in virtual screening 126
Totale 22742
Categoria #
all - tutte 47066
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 47066

Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/201832 0000 00 00 00032
2018/20192175 5533185171 23972 5562 68210402623
2019/20205611 4173543981358 372486 371647 400434221153
2020/20214930 251172283222 810410 415396 288598663422
2021/20225040 344591330625 38340 221194 977401014461
2022/20233945 29738468445 3661110 73368 4923729411
Totale 24680