New magnetically recoverable heterogeneous Pd-catalyst active in the alcoxycarbonylation of iodobenzene

Carbon-carbon bond formation is a long-standing challenge to organic chemists and several catalytic approaches have been developed during the past decades. Among these, the palladium-catalyzed carbonylation of aryl halides and their derivatives represents a powerful method for the synthesis of many aromatic compounds; especially, carboxylic acids and their derivatives. However, the difficult separation of the products from catalyst in the traditional homogeneous catalysis hinders sometimes its application in industrial process. This problem can be overcome by means of heterogeneous catalysis used nowadays in many industries to produce a variety of commercial products. Although in the heterogeneous catalysts the catalyst can be readily recovered usually by filtration or centrifugation catalyst recovery and reuse remain the two most important features for many green synthetic methods.Recently, new smart supports (magnetic nanoparticles, MNPs) have emerged and have great potential for catalyst recovery, because magnetic separation from the reaction mixture with an external permanent magnet is typically simpler and more effective than filtration or centrifugation as it prevents loss of the catalyst.