Schiff-bases and their dinuclear metal complexes have been extensively received special attention because of their wide range of applications including catalysts, medicine crystal engineering, anti-corrosion agent, and biological activities [1]. Dinuclear macrocyclic lead (II) complex, Pb2L1(SCN)4 was synthesized by template condensation of pyridine-2,6-dicarboxaldehyde and 1,2-bis (2-aminoethoxy) ethane in presence of Pb(SCN)2 as the metal source, here L1 is tetra-Schiff-base macrocycle. Transmetallation treatment of Pb2L1(SCN)4 with Co(PF6)2.6H2O produced the new complex, Co2L1(SCN)4 [2]. Reduction of lead (II) complex gave new reduced tetra-Schiff-base macrocyclic ligand, L2[3]. All the metal complexes and ligand were characterized by UV-Visible, FT-IR, 1H NMR spectroscopy. The antibacterial activities against some pathogenic gram positive and gram negative bacteria were studied by cylinder disk diffusion method. The complexes were found to inhibit the growth of bacteria.
Synthesis, Characterization and Antibacterial Activity on Dinuclear Schiff-base Macrocyclic Metal Complexes
ALAM, MD MAHBUBUL;
2014-01-01
Abstract
Schiff-bases and their dinuclear metal complexes have been extensively received special attention because of their wide range of applications including catalysts, medicine crystal engineering, anti-corrosion agent, and biological activities [1]. Dinuclear macrocyclic lead (II) complex, Pb2L1(SCN)4 was synthesized by template condensation of pyridine-2,6-dicarboxaldehyde and 1,2-bis (2-aminoethoxy) ethane in presence of Pb(SCN)2 as the metal source, here L1 is tetra-Schiff-base macrocycle. Transmetallation treatment of Pb2L1(SCN)4 with Co(PF6)2.6H2O produced the new complex, Co2L1(SCN)4 [2]. Reduction of lead (II) complex gave new reduced tetra-Schiff-base macrocyclic ligand, L2[3]. All the metal complexes and ligand were characterized by UV-Visible, FT-IR, 1H NMR spectroscopy. The antibacterial activities against some pathogenic gram positive and gram negative bacteria were studied by cylinder disk diffusion method. The complexes were found to inhibit the growth of bacteria.
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