Water soluble complexes derived from the interaction between Rh(CO)2(acac) and [Ir(COD)Cl]2, respectively, with human serum albumin (HSA), were employed in the aqueous biphasic hydrogenation of a,b-unsaturated compounds as 2-cyclohexen-1-one (I), 2-butenal (V), 3-phenyl-2-propenal (IX) and 3-aryl-2-methyl-2-propenals (XIII and XVII). Both catalytic systems Rh/HSA and Ir/HSA showed to be very active in the hydrogenation of ketone I even at low temperature and hydrogen pressure; in particular, the rhodium based catalyst showed to be very selective affording exclusively cyclohexanone (II). The a,b-unsaturated aldehydes investigated required higher temperature (up to 60 8C) and pressure (5 MPa) to obtain good conversions. In this case Rh/HSA resulted to bemore active than Ir based catalyst. In all cases both Rh/HSA and Ir/HSA were easily recycled without significant loss of activity.

Aqueous biphasic hydrogenations catalyzed by rhodium and iridium complexes modified with human serum albumin

MINELLO, FABIOLA;PAGANELLI, Stefano;PICCOLO, Oreste
2010

Abstract

Water soluble complexes derived from the interaction between Rh(CO)2(acac) and [Ir(COD)Cl]2, respectively, with human serum albumin (HSA), were employed in the aqueous biphasic hydrogenation of a,b-unsaturated compounds as 2-cyclohexen-1-one (I), 2-butenal (V), 3-phenyl-2-propenal (IX) and 3-aryl-2-methyl-2-propenals (XIII and XVII). Both catalytic systems Rh/HSA and Ir/HSA showed to be very active in the hydrogenation of ketone I even at low temperature and hydrogen pressure; in particular, the rhodium based catalyst showed to be very selective affording exclusively cyclohexanone (II). The a,b-unsaturated aldehydes investigated required higher temperature (up to 60 8C) and pressure (5 MPa) to obtain good conversions. In this case Rh/HSA resulted to bemore active than Ir based catalyst. In all cases both Rh/HSA and Ir/HSA were easily recycled without significant loss of activity.
File in questo prodotto:
File Dimensione Formato  
Applied Catalysis.pdf

non disponibili

Tipologia: Documento in Post-print
Licenza: Accesso chiuso-personale
Dimensione 151.48 kB
Formato Adobe PDF
151.48 kB Adobe PDF   Visualizza/Apri

I documenti in ARCA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10278/30031
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 20
  • ???jsp.display-item.citation.isi??? 20
social impact