A small library of dinuclear gold(i) complexes with the title ligands has been prepared, encompassing neutral, mono- and dicationic complexes. The luminescence properties of the complexes in the solid state have been evaluated, and it turns out that neutral and monocationic complexes not presenting a rigid metallamacrocyclic structure can exhibit rather strong emissions that extend towards the red region of the visible spectrum. Thein vitroanticancer activity of the complexes has been also preliminarly evaluated; cytotoxicity seems to correlate with complex lipophilicity, whereas selectivity towards cancer cells can be apparently enhanced upon a judicious choice of the ligands.

Dinuclear gold(i) complexes withN-phosphanyl, N-heterocyclic carbene ligands: synthetic strategies, luminescence properties and anticancer activity

Mauceri M.;Rizzolio F.
Membro del Collaboration Group
;
Accorsi G.;
2021-01-01

Abstract

A small library of dinuclear gold(i) complexes with the title ligands has been prepared, encompassing neutral, mono- and dicationic complexes. The luminescence properties of the complexes in the solid state have been evaluated, and it turns out that neutral and monocationic complexes not presenting a rigid metallamacrocyclic structure can exhibit rather strong emissions that extend towards the red region of the visible spectrum. Thein vitroanticancer activity of the complexes has been also preliminarly evaluated; cytotoxicity seems to correlate with complex lipophilicity, whereas selectivity towards cancer cells can be apparently enhanced upon a judicious choice of the ligands.
2021
50
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10278/3752652
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