In pursuing the origin of informational polymers, we followed the assumption that their spontaneous formation could only have occurred: (i) if all the components were present at the same site and in the same reaction, and (ii) if the thermodynamics of the processes involved favored a polymerized over a monomeric state of the precursors. A plausible scenario satisfying both assumptions is provided. © 2009 Elsevier Masson SAS. All rights reserved.
From formamide to RNA: the roles of formamide and water in the evolution of chemical information
CRESTINI, Claudia
2009-01-01
Abstract
In pursuing the origin of informational polymers, we followed the assumption that their spontaneous formation could only have occurred: (i) if all the components were present at the same site and in the same reaction, and (ii) if the thermodynamics of the processes involved favored a polymerized over a monomeric state of the precursors. A plausible scenario satisfying both assumptions is provided. © 2009 Elsevier Masson SAS. All rights reserved.
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