Home » Volume 32, 2017 » Issue No. 4 SPECIAL ISSUE ON LIGNIN Structural changes of lignin in biorefinery pretreatments and consequences to enzyme-lignin interactions - OPEN ACCESS Mika Henrikki Sipponen, Jenni Rahikainen, Timo Leskinen, Ville Pihlajaniemi, Maija-Liisa Mattinen, Heiko Lange, Claudia Crestini and Monika Österberg Abstract The main target of a biorefinery pretreatment process is to break down the lignin-reinforced plant cell wall structure prior to enzymatic hydrolysis of polysaccharides to fermentable sugars. Various physico-chemical alterations occur in lignin during the biomass pretreatment, but effects of those structural changes on subsequent enzymatic hydrolysis have remained ambiguous. We review the reinforcing and detrimental lignin-enzyme interactions and their underlying mechanisms, and use this structure-function information to assess critical features of current and emerging pretreatment technologies. Our perspective is that truly multidisciplinary research is needed to develop pretreatments that render lignin non-inhibiting to enzymes and with high potential for further valorisation.

Structural changes of lignin in biorefinery pretreatments and consequences to enzyme-lignin interactions

Crestini C;
2017-01-01

Abstract

Home » Volume 32, 2017 » Issue No. 4 SPECIAL ISSUE ON LIGNIN Structural changes of lignin in biorefinery pretreatments and consequences to enzyme-lignin interactions - OPEN ACCESS Mika Henrikki Sipponen, Jenni Rahikainen, Timo Leskinen, Ville Pihlajaniemi, Maija-Liisa Mattinen, Heiko Lange, Claudia Crestini and Monika Österberg Abstract The main target of a biorefinery pretreatment process is to break down the lignin-reinforced plant cell wall structure prior to enzymatic hydrolysis of polysaccharides to fermentable sugars. Various physico-chemical alterations occur in lignin during the biomass pretreatment, but effects of those structural changes on subsequent enzymatic hydrolysis have remained ambiguous. We review the reinforcing and detrimental lignin-enzyme interactions and their underlying mechanisms, and use this structure-function information to assess critical features of current and emerging pretreatment technologies. Our perspective is that truly multidisciplinary research is needed to develop pretreatments that render lignin non-inhibiting to enzymes and with high potential for further valorisation.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10278/3710321
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