Micellar media in water provide a simple and efficient environment to favor the multi-component synthesis of 1,2,3-triazoles from organic bromides, sodium azide and terminal alkynes in the presence of [Cu(IMes)Cl] 1 catalyst at room temperature within few hours. The micellar medium favors both the in situ formation of the organic azide and its metal promoted cycloaddition with the alkyne
Micellar media in water provide a simple and efficient environment favoring the multi-component synthesis of 1,2,3-triazoles from organic bromides, sodium azide and terminal alkynes in the presence of [Cu(IMes)Cl] 1 catalyst at room temperature within a few hours. The micellar medium favors both the in situ formation of the organic azide and its metal promoted cycloaddition with the alkyne.
Autori: | ||
Data di pubblicazione: | 2015 | |
Titolo: | Micellar Promoted Multi-Component Synthesis of 1,2,3-Triazoles in Water at Room Temperature | |
Rivista: | GREEN CHEMISTRY | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1039/c4gc02248c | |
Volume: | 17 | |
Appare nelle tipologie: | 2.1 Articolo su rivista |
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GreenChem2015 Triazoles.pdf | Documento in Post-print | Accesso chiuso-personale | Open Access Visualizza/Apri |