The synthesis of substituted 1H-tetrazoles from aliphatic or aromatic isonitriles and trimethylsilyl azide can be efficiently promoted by the hexameric capsule of resorcin[ 4]arene as a supramolecular self-assembled catalyst. The reaction is sensitive to the size and nature of the substrate and is driven by encapsulation of the reagents within the cavity of the supramolecular catalyst.

The synthesis of substituted 1H-tetrazoles from aliphatic or aromatic isonitriles and trimethylsilyl azide can be efficiently promoted by the hexameric capsule of resorcin[4]arene as a supramolecular self-assembled catalyst. The reaction is sensitive to the size and nature of the substrate and is driven by encapsulation of the reagents within the cavity of the supramolecular catalyst.

Supramolecular Catalysis in the Synthesis of Substituted 1H-Tetrazoles from Isonitriles by a Self-Assembled Hexameric Capsule

LA SORELLA, GIORGIO;SPERNI, Laura;FABRIS, Fabrizio;STRUKUL, Giorgio;SCARSO, Alessandro
2015

Abstract

The synthesis of substituted 1H-tetrazoles from aliphatic or aromatic isonitriles and trimethylsilyl azide can be efficiently promoted by the hexameric capsule of resorcin[ 4]arene as a supramolecular self-assembled catalyst. The reaction is sensitive to the size and nature of the substrate and is driven by encapsulation of the reagents within the cavity of the supramolecular catalyst.
File in questo prodotto:
File Dimensione Formato  
ajoc.201402229.pdf

accesso aperto

Descrizione: This is the peer reviewed version of the following article: Supramolecular Catalysis in the Synthesis of Substituted 1H-Tetrazoles from Isonitriles by a Self-Assembled Hexameric Capsule], which has been published in final form at https://onlinelibrary.wiley.com/doi/full/10.1002/ajoc.201402229 This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Tipologia: Documento in Pre-print
Licenza: Accesso gratuito (solo visione)
Dimensione 537.3 kB
Formato Adobe PDF
537.3 kB Adobe PDF Visualizza/Apri

I documenti in ARCA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10278/3627897
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 28
  • ???jsp.display-item.citation.isi??? 26
social impact