Efficient nitrile hydration to the corresponding amide derivatives is observed in water using poorly soluble [RuCl2(η6- arene)(PR3)] catalysts 1 with the aid of surfactants to ensure substrate and catalyst solubilization, and enabling ligand effect study on catalytic activity. Amide yields of 40 to 95% can be observed with a variety of aromatic and aliphatic nitriles using the optimized catalyst system, [RuCl 2(p-cymene)(PPh2OEt)]/Triton X-114. Catalyst separation and recycling is possible.

Efficient Nitrile Hydration Mediated by Ru(II) Catalysts in Micellar Media

CAVARZAN, Alessandra;SCARSO, Alessandro;STRUKUL, Giorgio
2010-01-01

Abstract

Efficient nitrile hydration to the corresponding amide derivatives is observed in water using poorly soluble [RuCl2(η6- arene)(PR3)] catalysts 1 with the aid of surfactants to ensure substrate and catalyst solubilization, and enabling ligand effect study on catalytic activity. Amide yields of 40 to 95% can be observed with a variety of aromatic and aliphatic nitriles using the optimized catalyst system, [RuCl 2(p-cymene)(PPh2OEt)]/Triton X-114. Catalyst separation and recycling is possible.
2010
5
File in questo prodotto:
File Dimensione Formato  
reprint.pdf

non disponibili

Tipologia: Documento in Post-print
Licenza: Accesso chiuso-personale
Dimensione 121.84 kB
Formato Adobe PDF
121.84 kB Adobe PDF   Visualizza/Apri

I documenti in ARCA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10278/3596
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 60
  • ???jsp.display-item.citation.isi??? 57
social impact