This paper is focused on alkylphenols, compounds which are formed by the biodegradation of polyethoxilatedalkylphenols detergents. Our experiments show that alkylphenols act not only as detergents, butalsoasuncouplersoftheoxidativephosphorylation. Thiseff~ot,canbeobservedatverylowdoses,thus suggesting that the preferential target ofnonylphenols in living organisms are mitochondria.

An in vitro study on the toxic effects of nonylphenols (NP) in mitochondria

BRAGADIN, Marcantonio;PERIN, Guido;MANENTE, Sabrina;
1999

Abstract

This paper is focused on alkylphenols, compounds which are formed by the biodegradation of polyethoxilatedalkylphenols detergents. Our experiments show that alkylphenols act not only as detergents, butalsoasuncouplersoftheoxidativephosphorylation. Thiseff~ot,canbeobservedatverylowdoses,thus suggesting that the preferential target ofnonylphenols in living organisms are mitochondria.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/10278/35556
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