Benzotriazole forms with amines stable complexes that in some cases separate spontaneously as crystals from solutions of polar organic solvents. The stoichiometries and the binding constants of these complexes have been determined by 1H NMR analysis in deuterochloroform. The quantitative analysis of the equilibria involved in thecomplexation process sheds light on the behaviour of benzotriazoles in solutions and gives an estimate of the influence of allosteric effects when multiple interactions are present.

Cooperativity in benzotriazole-amine complexes: allosteric tuning of molecular recognition interfaces

DE LUCCHI, Ottorino;
2011-01-01

Abstract

Benzotriazole forms with amines stable complexes that in some cases separate spontaneously as crystals from solutions of polar organic solvents. The stoichiometries and the binding constants of these complexes have been determined by 1H NMR analysis in deuterochloroform. The quantitative analysis of the equilibria involved in thecomplexation process sheds light on the behaviour of benzotriazoles in solutions and gives an estimate of the influence of allosteric effects when multiple interactions are present.
File in questo prodotto:
File Dimensione Formato  
POC_2011_24_122.pdf

non disponibili

Tipologia: Documento in Post-print
Licenza: Accesso chiuso-personale
Dimensione 392.8 kB
Formato Adobe PDF
392.8 kB Adobe PDF   Visualizza/Apri

I documenti in ARCA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10278/26339
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 2
social impact