The interactions of methylmercury with rat liver lysosomes were investigated. The results indicate that methylmercury enhances the proton permeability in membranes. Since this uncoupling mechanism necessarily implies the transport of a charged ion (in this case CH3Hg) through the membrane, this fact can help to explain why a preferential target of methylmercury are nerve cells, whose plasma membrane potential has the highest value, when compared with other cells.
The interaction of Methylmercury with Lysosomes from rat liver
BRAGADIN, Marcantonio;MANENTE, Sabrina;
2002-01-01
Abstract
The interactions of methylmercury with rat liver lysosomes were investigated. The results indicate that methylmercury enhances the proton permeability in membranes. Since this uncoupling mechanism necessarily implies the transport of a charged ion (in this case CH3Hg) through the membrane, this fact can help to explain why a preferential target of methylmercury are nerve cells, whose plasma membrane potential has the highest value, when compared with other cells.
File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
Methylmercury and Lysosome.pdf
accesso aperto
Tipologia:
Documento in Post-print
Licenza:
Accesso gratuito (solo visione)
Dimensione
114.66 kB
Formato
Adobe PDF
|
114.66 kB | Adobe PDF | Visualizza/Apri |
I documenti in ARCA sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
